Hebrews 10:10

By which will we are sanctified. By this complete submission our sins are removed from us and we are made holy. The meaning of "sanctified" here is remission of sin.

Through the offering of the body of Jesus Christ. In Christ's surrender his body was offered on the cross, once [for all] for sin, and by that offering our sins are remitted.

Hebrews 10:29

Of how much sorer punishment. Where much is given much is required. How great the sin of the apostate!

Who hath trodden under foot the Son of God. Despised him instead of Moses.

And hath counted the blood of the covenant. the blood of Christ, the blood by which he was sanctified.

Wherewith he was sanctified. Cleansed from the guilt of sin,

An unholy thing. Treated this blood as if it was unholy.

And hath done despite unto the Spirit of grace. Rejected all the work, the words, the preaching, the pleadings of the Holy Spirit.
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